Fluorodopa f 18
Fluorodopa F (fluorodopa f 18) is a small molecule pharmaceutical. Fluorodopa f 18 was first approved as Fluorodopa f18 on 2019-10-10.
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Commercial
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FDA
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| fluorodopa | New Drug Application | 2021-01-15 |
Indications
FDA
EMA
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Agency Specific
FDA
EMA
Expiration | Code | ||
|---|---|---|---|
FLUORODOPA F-18, FLUORODOPA F18, FEINSTEIN | |||
| 2024-10-10 | NCE, W | ||
Patent Expiration
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HCPCS
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Clinical
Clinical Trials
2234 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alzheimer disease | D000544 | EFO_0000249 | F03 | 13 | 13 | 9 | 5 | 6 | 43 |
| Postoperative cognitive complications | D000079690 | — | — | — | — | — | 1 | — | 1 |
| Familial amyloid neuropathies | D028227 | — | E85.1 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cognitive dysfunction | D060825 | — | G31.84 | 3 | 4 | 3 | — | 2 | 11 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | 1 | 3 | 1 | — | 1 | 4 |
| Neurodegenerative diseases | D019636 | EFO_0005772 | G31.9 | — | 2 | 1 | — | 1 | 3 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lewy body disease | D020961 | EFO_0006792 | G31.83 | 1 | 1 | — | — | 1 | 2 |
| Traumatic brain injuries | D000070642 | — | S06 | 1 | 1 | — | — | — | 2 |
| Frontotemporal dementia | D057180 | — | G31.0 | 1 | 1 | — | — | — | 2 |
| Chronic traumatic encephalopathy | D000070627 | — | — | — | 1 | — | — | — | 1 |
| Dementia | D003704 | EFO_0003862 | F03 | 1 | 1 | — | — | — | 1 |
| Depression | D003863 | — | F33.9 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 2 | — | — | — | — | 2 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | 1 | — | — | — | 1 | 2 |
| Neoplasms | D009369 | — | C80 | 1 | — | — | — | — | 1 |
| Progressive supranuclear palsy | D013494 | EFO_0002512 | G23.1 | 1 | — | — | — | — | 1 |
| Corticobasal degeneration | D000088282 | — | G31.85 | 1 | — | — | — | — | 1 |
| Pick disease of the brain | D020774 | EFO_0003096 | G31.01 | 1 | — | — | — | — | 1 |
| Cognition disorders | D003072 | — | — | 1 | — | — | — | — | 1 |
| Drug-related side effects and adverse reactions | D064420 | — | T88.7 | 1 | — | — | — | — | 1 |
| Radiation exposure | D000069079 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | — | — | 1 | 1 |
| Cerebral hemorrhage | D002543 | — | — | — | — | — | — | 1 | 1 |
| Cerebral amyloid angiopathy | D016657 | EFO_0006790 | I68.0 | — | — | — | — | 1 | 1 |
| Neurocognitive disorders | D019965 | — | F09 | — | — | — | — | 1 | 1 |
| Healthy volunteers/patients | — | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Fluorodopa f 18 |
| INN | fluorodopa (18f) |
| Description | 6-((18)F)fluoro-L-dopa is a 6-fluoro-L-dopa and a (18)F radiopharmaceutical. |
| Classification | Small molecule |
| Drug class | dopamine receptor agonists |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | N[C@@H](Cc1cc(O)c(O)cc1[18F])C(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 92812-82-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3400972 |
| ChEBI ID | 49166 |
| PubChem CID | 56494 |
| DrugBank | DB13848 |
| UNII ID | 2C598205QX (ChemIDplus, GSRS) |
Target
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Trends
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Safety
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Adverse Events
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39 adverse events reported
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